Progesterone Cream

It's considered for women whose symptoms and lab work point to low progesterone, often disrupted sleep, cycle changes, or mood changes during perimenopause and menopause, and for those who prefer a topical option to a capsule. It isn't right for everyone. A licensed clinician reviews your labs, history, and current medications before deciding whether it's appropriate for you.

Progesterone is a hormone the body makes naturally, and levels shift across the menstrual cycle and fall during the menopause transition. Applied to the skin, compounded progesterone is absorbed through it and into the bloodstream, which may help support the balance your clinician is aiming for. Your clinician decides the form and amount from your labs, symptoms, and the rest of your plan.

It's applied to clean, dry skin at the sites your clinician specifies, rotating between them so one area isn't used repeatedly. Most plans call for daily use on a schedule your clinician sets. Wash your hands after each application, and until the cream has fully absorbed keep the area covered and avoid skin-to-skin contact with others, especially children and partners.

Yes. Lab work comes before a prescription: it helps confirm what's driving your symptoms, establishes your baseline, and flags anything that would make hormone therapy unsafe for you. Your clinician also uses follow-up labs and check-ins to see how you're responding and adjust the plan. Progesterone cream isn't prescribed without labs and a clinician review.

Side effects may include irritation where the cream is applied, drowsiness, breast tenderness, headache, or mood changes. Progesterone is generally avoided if you have a history of breast cancer, blood clots, liver disease, or unexplained vaginal bleeding. If you also take estrogen, your clinician decides whether a cream gives enough uterine protection or another form is needed, and monitors you throughout.

You can cancel anytime from your online patient portal. There are no cancellation fees or long-term contracts. Canceling won't stop an order already sent to the pharmacy. If your order is still pending, contact support and we'll help.